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Accueil > Animation scientifique > Seminaires passés

Séminaire de Dr Sjoerd de Vries vendredi 18 septembre 2015 à 11h00 à l’Université Lille 1 - bâtiment C9 - Salle André Verbert

Integrative modelling of protein complexes with ATTRACT

Dr Sjoerd de Vries
Technische Universitat, Munchen
Computational assembly of protein complexes

Abstract

Protein complexes are essential therapeutic targets in a large variety of biological processes. ATTRACT is a versatile engine for the modelling of protein complexes from semi-rigid components : proteins, domains, peptides, nucleic acids, and other molecules. Key features of ATTRACT are its coarse-grained force field, multiple strategies to incorporate structural flexibility, experimental restraints, and the simultaneous assembly of many components. Moreover, ATTRACT has dedicated protocols for cryo-EM data (ATTRACT-EM), single-stranded RNA, and protein-peptide docking (pepATTRACT). ATTRACT is accessible through a user-friendly web interface :
(http://www.attract.ph.tum.de/services/ATTRACT/attract.html)